RU-58841 50MG PER ML

RU-58841, also known as PSK-3841 or HMR-3841, is a non-steroidal anti-androgen compound primarily developed for the treatment of androgen-dependent conditions such as acne, androgenic alopecia (male pattern baldness), and hirsutism. Unlike other anti-androgens, RU-58841 works locally, meaning it is designed to be applied topically to minimize systemic side effects.

Chemical Structure and Properties:

• Chemical Name: 4-[3-(4-hydroxybutyl)phenyl]-3,5-dihydroxy-2-(trifluoromethyl)benzonitrile
• Molecular Formula: C17H18F3NO3
• Molecular Weight: 341.33 g/mol
• Class: Non-Steroidal Anti-Androgen (NSAA)
• Form: Typically available in liquid or topical solution form

Mechanism of Action: RU-58841 works by binding to androgen receptors in hair follicles and sebaceous glands, blocking the effects of dihydrotestosterone (DHT), a potent androgen responsible for conditions like androgenic alopecia and acne. By inhibiting DHT from binding to these receptors, RU-58841 helps reduce hair loss and acne without affecting systemic androgen levels.

Development and Purpose: RU-58841 was developed as a topical treatment for androgen-related conditions to provide effective results with reduced systemic side effects compared to oral anti-androgens. It has been researched primarily for its applications in treating male pattern baldness and acne.

 Benefits of RU-58841

• Prevention of Hair Loss: RU-58841 is effective in reducing hair loss by blocking DHT from binding to androgen receptors in hair follicles, thereby preventing follicular miniaturization.

• Promotion of Hair Regrowth: By inhibiting the action of DHT, RU-58841 can promote the regrowth of hair in areas affected by androgenic alopecia.

• Minimal Systemic Side Effects: As a topical solution, RU-58841 is designed to act locally, minimizing systemic absorption and reducing the risk of side effects associated with oral anti-androgens.

• Improvement in Hair Density: Users often report an increase in hair density and thickness, leading to a fuller appearance.

• Reduction in Acne: RU-58841 can help reduce acne by inhibiting androgen receptors in sebaceous glands, thus decreasing sebum production and the formation of acne lesions.

• Non-Hormonal Treatment Option: RU-58841 offers a non-hormonal alternative for treating androgen-dependent conditions, making it suitable for individuals who cannot tolerate hormonal therapies.

• Potential Treatment for Hirsutism: In addition to its effects on hair loss and acne, RU-58841 may help reduce unwanted hair growth (hirsutism) by blocking androgen receptors in hair follicles.

• Minimal Impact on Sexual Function: Due to its localized action, RU-58841 is less likely to affect sexual function, a common side effect of systemic anti-androgens.

• Rapid Onset of Action: Users may begin to see improvements in hair growth and acne reduction within a few weeks of starting treatment with RU-58841.

• Compatibility with Other Treatments: RU-58841 can be used in conjunction with other treatments, such as minoxidil for hair growth or topical retinoids for acne, to enhance overall efficacy.

RU-58841 is a promising topical anti-androgen that offers significant benefits for individuals suffering from androgen-dependent conditions such as androgenic alopecia and acne. Its localized action helps minimize systemic side effects, making it a safer alternative to oral anti-androgens. Despite its potential, it is important to note that RU-58841 is primarily used in research settings, and its long-term safety and efficacy in humans are not fully established.