GW-0742 30MG PER ML

GW-0742, also known as GW610742, is a synthetic compound belonging to the class of peroxisome proliferator-activated receptor delta (PPARδ) agonists. It is closely related to GW501516 (Cardarine) and is primarily investigated for its potential benefits in enhancing endurance, improving metabolic health, and offering cardiovascular protection.

Chemical Structure and Properties:

• Chemical Name: 2-Methoxy-4-((4-(trifluoromethyl)phenyl)methoxy)-N-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)benzamide
• Molecular Formula: C21H17F6N3O3S
• Molecular Weight: 503.43 g/mol
• Class: PPARδ Agonist
• Form: Typically available in liquid or capsule form for research purposes

Mechanism of Action: GW-0742 works by activating the PPARδ receptor, which plays a key role in regulating lipid metabolism, energy homeostasis, and inflammatory responses. Activation of PPARδ leads to increased fatty acid oxidation, improved insulin sensitivity, and enhanced energy expenditure.

Development and Purpose: GW-0742 was developed to investigate its potential in treating metabolic disorders, cardiovascular diseases, and other conditions associated with dysregulated lipid metabolism. Its primary applications in research focus on its effects on endurance, metabolic health, and cardiovascular protection.

Benefits of GW-0742

• Enhanced Endurance: GW-0742 is known to increase endurance by promoting the utilization of fatty acids for energy, which can enhance athletic performance and stamina.

• Improved Metabolic Health: By activating PPARδ, GW-0742 can improve lipid profiles, reduce triglycerides, and enhance insulin sensitivity, contributing to overall metabolic health.

• Cardiovascular Protection: GW-0742 has shown potential in protecting against atherosclerosis and other cardiovascular diseases by reducing inflammation and improving lipid metabolism.

• Fat Loss: The compound promotes the oxidation of fatty acids, aiding in the reduction of body fat and supporting weight loss efforts.

• Anti-inflammatory Effects: GW-0742 can reduce inflammation by modulating the expression of inflammatory cytokines and other markers of inflammation.

• Muscle Preservation: It helps in preserving lean muscle mass during periods of calorie restriction or intense physical activity by promoting efficient energy utilization.

• Improved Lipid Profile: GW-0742 can positively affect cholesterol levels by increasing HDL (good cholesterol) and reducing LDL (bad cholesterol) levels.

• Neuroprotective Effects: Research suggests that GW-0742 may have neuroprotective properties, potentially offering benefits in conditions like Alzheimer's disease and other neurodegenerative disorders.

• Increased Mitochondrial Biogenesis: The activation of PPARδ can stimulate the production of new mitochondria, improving cellular energy production and overall metabolic efficiency.

• Potential in Treating Metabolic Syndrome: GW-0742 shows promise in addressing various components of metabolic syndrome, including obesity, insulin resistance, hypertension, and dyslipidemia.

GW-0742 is a potent PPARδ agonist with a range of potential benefits, particularly in enhancing endurance, improving metabolic health, and offering cardiovascular protection. Its ability to promote fatty acid oxidation, improve lipid profiles, and reduce inflammation makes it a promising compound for various therapeutic applications. However, it is important to note that GW-0742 is still primarily used in research settings, and its long-term safety and efficacy in humans are not fully established.